1Department of Chemistry, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India
2Amrita Centre for Advanced Research in Ayurveda Lab, School of Ayurveda, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India
*Corresponding Author E-mail: zeenaspillai@am.amrita.edu
Silver nanoparticles (AgNPs) have gained considerable attention owing to their broad biomedical applications and therapeutic potential. In this study, AgNPs were synthesized via a green route using Curcuma angustifolia leaf extract, which serves as both reducing and stabilizing agent. The nanoparticles were characterized by UV– Visible spectroscopy, which showed a characteristic surface plasmon resonance at 430 nm, and by XRD and TEM analyses. TEM revealed well-dispersed, flower-like nanoparticles, while XRD confirmed their crystalline nature. The antioxidant potential of the AgNPs, evaluated using the Ferric Reducing Antioxidant Power (FRAP) assay, indicated strong radical scavenging activity. In addition, the biosynthesized AgNPs exhibited dose-dependent anticancer activity against Hep-G2 liver cancer cells. These findings suggest that Curcuma angustifolia-mediated AgNPs possess promising antioxidant and anticancer properties, supporting their potential application in biomedical therapeutics.
AgNPs, Green synthesis, Anticancer activity, Antioxidant activity, Curcuma angustifolia
