1Department of Pharmaceutical Sciences, NIMS University, Jaipur, Rajasthan, India
2Department of Pharmaceutical Chemistry, NIMS Institute of Pharmacy, NIMS University, Jaipur, Rajasthan, India
3RITEE College of Pharmacy, Raipur, Chhattisgarh, India
*Corresponding Author E-mail: meherpharm@gmail.com
Boerhavia diffusa andAsparagus racemosus plant extracts were evaluated for antidiabetic effects in STZ-lowdosed and high-fat diet induced diabetic rats. Rats weighing between 200 - 250g are selected for antidiabetic activity and divided randomly in to six groups normal control, diabetic Control, standard control (glibenclamide, 2.5mg/kg), Boerhavia diffusa extract (200mg/kg), Asparagus racemosus extract (200mg/kg), one group with both the test drug with five animals in each group. High-fat diet was initially given for 4 weeks. Low-dose STZ, i.e, 35mg/kg, was given for the induction of diabetes. Treatment was given for 15 days. Results show a significant (P˂0.05) improvement when compared with the diabetic control group.
Boerhavia diffusa, Asparagus recemosus, Antidiabetic, Lipid profile, Glycogen
