Progressive Agriculture
  • Year: 2021
  • Volume: 21
  • Issue: 1

Nucleotide sequence analysis of phenylketonuria using matlab

1Sardar Vallabhbhai Patel University of Agriculture and Technology, Meerut, Uttar Pradesh, India

2Government Girls Ploytechnic, Bareilly, Uttar Pradesh, India

3Invertis University, Bareilly, Uttar Pradesh, India

Online published on 18 October, 2021.

Abstract

Phenylketonuria (PKU) is a genetic disorder inherited from a person's parents (2). In PKU, thephenylalanine can build up to harmful levels in the body, causing intellectual disability and otherserious health problems. In this paper we find the nucleotide sequence of both, a Phenylketonuria (PKU)patients and a homo sapiens (normal human) and then compare their nucleotide density and codon countwith the help of MATLAB functions. We find that in nucleotide sequence and Base count of affectedphenylketonuria disease patient is different from a normal homo sapiens. Thymine is more in affectedperson than normal person.

Keywords

Phenylketonuria, Phenylalanine, Thymine