Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar- 143005
*Corresponding author's email: swab2002@yahoo.com
Online published on 1 May, 2014.
Antimutagenic and antioxidative potential of Chlorophytum borivilianum was investigated by taking methanol extract of the peels of its tubers. While antimutagenic property of the extract was evaluated using Ames assay, its antioxidant activity was determined through 1, 1-diphenyl-2-picryl hydrazyl free radical scavenging, deoxyribose degradation, reducing power, chelating power and lipid peroxidation assays. The methanol extract showed significant antimutagenic effect in both the co-incubation and pre-incubation modes. The extract also showed strong inhibitory activity in DPPH free radical scavenging, site and non-site specific deoxyribose degradation, as well as in lipid peroxidation assays. The reducing power and chelating power assays were non-significant. The study established the antimutagenic and antioxidative potential of tuber peels of C. borivilianum.
Antimutagenic activity, Antioxidant activity, Ames assay, Free radicals, Mutagens