1Assistant Professor, Department of Physiology, Pacific Institute of Medical Sciences, Udaipur, Rajasthan
2Professor, Department of Physiology, Darbhanga Medical College, Laheriasarai, Bihar
3Assistant Professor, Department of Medicine, SKBS Medical College & Research Centre, Vadodara, Gujrat
4Senior Resident, IGIMS, Patna, Bihar
5Professor & Head, Department of Physiology, Darbhanga Medical College, Laheriasarai, Bihar
6Assistant Professor, Department of Physiology, Vardman Institute of Medical Sciences, Pawapuri
Online published on 30 December, 2015.
Kidney plays very importantrole in maintaining homeostasis, being functional unit of kidney, nephron is responsible for this. In certain diseases such as nephrotic and nephritic syndromes, renal involvement leads to edema. Edema can occur either due to sodium retention or hypoalbuminemia. The presentation of glomerular disease and the biochemical profile differs with region, race and also has shown change with changing times.
We investigated the biochemical profile in patients of glomerular diseases having edema in north Bihar region and also explored the role of serum albumin in edema genesis.
In our study, we recruited the diagnosed patients of nephrotic and nephritic syndrome of either gender in the age group of 03–30 years presenting with edema. They underwent blood investigations including blood urea, serum creatinine, serum cholesterol, serum albumin, erythrocyte sedimentation rate, total leukocyte count. Systolic and diastolic blood pressure was also measured in all patients.
Serum albumin level isinversely proportional to edema, but more consistently in patient of nephrotic syndrome rather than nephritic syndrome.
Nephrotic syndrome, Nephritic syndrome, Edema
