Therapeutic potential of honey bee collected pollen and beebread of Brassica campestris: A target against oxidative stress induced by Salmonella enterica serovar Typhimurium in mice

Multidrug resistance (MDR) among microbes are threatening our ability to treat common infectious diseases including typhoid, resulting in organ damages and finally death. Due to MDR, there is requirement to explore the natural products against infectious diseases. The present studies investigate the antioxidant effects of honey bee collected pollen and beebread against oxidative stress induced by Salmonella enterica serovar Typhimurium in BALB/c mice. Animals were divided into 8 groups: Group (Gp)1 was the normal control, Gp2 was infected with S. typhimurium, Gp3 was oral administration of bee pollen without infection, Gp4 was Salmonella infected and treated with bee pollen, Gp5 was given beebread without infection, Gp6 was Salmonella infected and treated with beebread, Gp7 was oral administration of vitamin C without infection and Gp8 Salmonella infected and treated with vitamin C. Animals were scarified after 21 days and biochemical investigations of liver, spleen, kidney and sera were performed. The experimental data showed significant differences in honey bee products and vitamin C treated groups as compared to the infected group. These results indicate the ameliorative effect of honey bee products on S. typhimurium induced oxidative stress in mice.