1Associate Professor, Department of Environmental Microbiology, School for Environmental Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Lucknow-226025, Uttar Pradesh, India
2Assistant Professor, Department of Microbiology, Institute of Bioscience and Biotechnology, Chhatrapati Sahu Ji Maharaj University, Kanpur-208024, Uttar Pradesh, India
*Corresponding author E-mail: sadhanasagar58@gmail.com
Online published on 21 January, 2017.
Biofilm is a complex community of microorganisms in which microbes are embedded in a matrix of exopolymeric substances (EPS). EPS of biofilm render three-dimensional organisation and provides protection against environmental stresses. Biofilms formed on abiotic as well as on biotic surfaces lead to acute or chronic infections. Biofilm-associated infections are very fiddly to control by antimicrobials because of knotty organisation ofbiofilm. The better consideration about the biofilm organisation lends a hand to find out novel techniques to control over them. In this review, we have illustrated the complexity ofbiofilm as well as its regulatory mechanism and control mechanisms.
Biofilm, Signalling molecule, Bacteriophage, Quorum sensing, Bacteria
