Division of Bacteriology and Mycology, Indian Veterinary Research Institute, Izatnagar - 243 122, (UP).
*Corresponding author: E-mail: chaturvedi.vk@mail.com
1Department of Molecular Medicine, University of Texas Health Science Center, San Antonio, Texas, USA, 78229.
The purified capsular polysaccharide of Pasteurella multocida B:2 was conjugated with bovine serum albumin by reductive amination and the immune response elicited in rabbit by conjugate vaccine was studied. The conjugate was immunogenic while the capsular polysaccharide and the non-conjugated capsular polysaccharide with BSA failed to elicit any protective immune response. The conjugate vaccine was able to afford 66% protection on challenge with P. multocida B:2.
