1Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia
*Corresponding Author: Hossam M. Aljawdah, Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia, Email: haljawdah@ksu.edu.sa
Online Published on 06 February, 2026.
Traditional medicine has utilized plant bioactive compounds for the treatment of prevalent diseases. Antioxidants play a protective role against free radicals. The high concentration of phytochemicals in C. spinosa establishes it as a model species for the extraction of bioactive compounds. The genus Coccidia significantly contributes to intestinal issues in conventional rabbit husbandry.
The total of phenols, flavonoids, flavonols and tannins in the extract of C. spinosa was quantified. The antioxidant activity of CS extract was evaluated in vitro through DPPH assays and the IC50 values were established. In vitro anticoccidial activity was assessed using five concentrations of CS extract. The inhibition of sporulated oocysts of the extract was assessed at 96 hours.
Chemical analysis of extract of C. spinosa showed that it contains a good percentage of the phenols, flavonoids, flavonols and tannins, the highest concentration of which was phenols. The extract had good antioxidant properties, with inhibition rates ranging from 79.142% to 7.952% at concentrations from 1000 to 31.25 μg/mL. The IC50 value was found to be 440.237 μg/mL. The anticoccidial effects were evaluated in vitro, revealing that oocysts exhibited the highest level of inhibition at concentrations of 100 mg/mL, 50 mg/mL and the reference drug.
Anticoccidial, Antioxidant, Capparis spinosa, Eimeria magna, Phytochemical
