Indian Journal of Animal Research
SCOPUSWeb of Science
  • Year: 2026
  • Volume: 59
  • Issue: 5

Lycopene Supplement Restores the Oxidation/Antioxidation Balance Through Efficient Antioxidant Activities in Wistar Rats with Cadmium-induced Oxidative Stress

  • Author:
  • Mohammed Al-Zharani1, Mohammed Mubarak1*, Hassan Rudayni1, Nada H. Aljarba2, Saad Alkahtani3, Fahd A. Nasr1, Mohammed S. Al-Eissa1
  • Total Page Count: 6
  • Page Number: 785 to 790

1Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh11623, Saudi Arabia.

2Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh11671, Saudi Arabia.

3Department of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.

*Corresponding Author: Mohammed Mubarak, Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh11623, Saudi Arabia. Email: mohammedahmed_62@yahoo.com

Abstract

Lycopene is a phytochemical exhibiting a wide range of health benefits and bioactivities. The present study focuses on lycopene’s in vivo antioxidant properties and evaluates the efficiency of dietary lycopene supplements in alleviating cadmium- induced oxidative stress.

The experimental rats were divided randomly into four groups (n=20): untreated control, lycopene-treated, cadmium- exposed and cadmium-lycopene groups.

The cadmium-exposed and Lycopene-accessed rats revealed improvements in both haematological and biochemical profiles. It was concluded that the efficient antioxidant properties of lycopene significantly help alleviate the alterations of the cadmium- induced oxidative stress.

Keywords

Antioxidant, Biochemical profile, Cadmium toxicity, Lycopene, Oxidative stress