1Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh11451, Saudi Arabia
*Corresponding Author: Mutee Murshed, Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh11451, Saudi Arabia, Email: Mmurshed@ksu.edu.sa
Online published on 23 January, 2026.
Plant products are reliable sources of traditional and contemporary medications for animals. This study aimed to investigate the effect of Calotropis procera on Eimeria perforans oocysts that infection rabbits.
Twelve well-plates of 3 ml containing 1×103 unsporulated oocysts were exposed to six treatments: 2.5% potassium dichromate solution as the non-treated control, four concentrations of C. procera extract (12.5, 25, 50 and 100 mg/mL) and toltrazuril 25 mg/mL as traditional medicine.
The mixture was examined (after 24, 48, 72 and 96 hours) for oocysticidal activity. The extract exhibited notable inhibition of E. perforans oocysts at 100 mg/mL doses, with suppression rates of approximately 89% after 96 h, nearly similar to the utilized reference drug, toltrazuril. The inhibitory rate increased with extended incubation duration and a high concentration ratio. The current study suggests that C. procera extract possesses inhibitory properties against oocyst sporulation.
C. procera, Destructive, E. perforans, Oocysticidal, Oryctolagus cuniculus
