Indian Journal of Animal Research
SCOPUSWeb of Science
  • Year: 2024
  • Volume: 58
  • Issue: 6

Investigating the impact of Launaea angustifolia extract on the reproduction function of female rats

  • Author:
  • Aiman A. Ammari1,*, Ahmad R. Alhimaidi1, Ramzi A. Amran1, Ahmed Rady1
  • Total Page Count: 5
  • Page Number: 930 to 934

1Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Kingdom of Saudi Arabia

*Corresponding Author: Aiman A. Ammari, Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Kingdom of Saudi Arabia, Email: aammari@ksu.edu.sa

Online published on 1 October, 2024.

Abstract

The purpose of this study is to investigate the effects of Launaea angustifolia methanol extract on the reproductive organs of female rats through the use of chemical screening.

A total of twenty-five female rats were separated into five distinct groups to be examined. The group that served as the control did not receive any dose, whereas the group that served as the negative control received DEMSO by oral gavage. Group 10 received 10 mg/kg body weight per day, Group 50 received 50 mg/kg body weight per day and Group 100 received 100 mg/kg body weight per day for a period of two weeks.

Despite the fact that the body weights of female rats rose during the course of this investigation, there were no significant variations between the groups after 14 days of dosing occurred. In the case of female rats, the body weights of the control group were found to be considerably greater (P<0.05) in all experimental days, with the exception of day 1 and day 3, when compared to the groups that received 50 and 100 mg. Although there was a discernible rise in the weight of the ovary in the control group in comparison to the group that was exposed to DMSO.

Keywords

Extract, Female, Hormonal, Launaea angustifolia