Indian Journal of Animal Research
SCOPUSWeb of Science
  • Year: 2024
  • Volume: 58
  • Issue: 4

Investigation of microbiological, physiological and histopathological changes in polymicrobial infection in old rats

  • Author:
  • U. Ulker1,*, S. Kizil2, B. Bayraktar3, M.E. Alcigir4, O. Kul4, H. Kaya5, H. Urusan6, S. Aydemir7, G.C. Kotan7, A.U. Onel2, E.M. Cecen2, G. Yaldiz2
  • Total Page Count: 7
  • Page Number: 628 to 634

1Department of Microbiology, Veterinary Faculty, Yozgat Bozok University, Yozgat, Turkiye

2Department of Microbiology, Veterinary Faculty, Kirikkale University, Kirikkale, Turkiye

3Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Bayburt University, Bayburt, Turkiye

4Department of Pathology, Veterinary Faculty, Kirikkale University, Kirikkale, Turkiye

5Department of Veterinary Medicine, Kelkit Aydin Dogan Vocational School, Gumushane University, Gumushane, Turkiye

6Vocational School of Technical Sciences, Ataturk University, Erzurum, Turkiye

7Department of Veterinary Medicine, Corum Alaca Vocational School, Hitit University, Corum, Turkiye

*Corresponding Author: U. Ulker, Department of Microbiology, Veterinary Faculty, Yozgat Bozok University, Yozgat, Turkiye, Email: ufukmulker@yahoo.com

Online published on 13 August, 2024.

Abstract

The aim of this study is to examine the microbiological, clinical, physiological and pathological findings of natural polymicrobial infection developing in a wistar rat colony under long-term observation.

In this study, 70 male Wistar albino rats, 3 years old, raised by conventional methods and housed in a cage environment were used. Thirteen rats with clinical symptoms such as torticollis and rotation were sacrificed for microbiological and histopathological examination after 14 days. For microbiological examination, the rapid diagnostic kit BBL Crystal system was used to identify bacterial agents in tissue and stool samples and the traditional culture method was used for isolation.

As a result of microbiological analysis, the rarely isolated Staphylococcus capitis (S. capitis) was isolated. Different Staphylococcus spp. It has been determined that the species can cause suppurative meningoencephalitis as well as septicemia in the brains of experimental animals., it is thought that polymicrobial infection will be useful for the identification of bacterial agents and infection prevention and treatment strategies.

Keywords

Physiological and pathologic findings, Polymicrobial infection, Rat, Staphylococcus capitis