1Department of Veterinary Medicine, College of Veterinary and Animal Sciences, G.B. Pant University of Agriculture and Technology, Pantnagar-263 145, Uttarakhand, India
*Corresponding Author: Jyoti Chanda Kalita, Department of Veterinary Medicine, College of Veterinary and Animal Sciences, G.B. Pant University of Agriculture and Technology, Pantnagar, 263 145, Uttarakhand, India, Email: jyoti696b@gmail.com
Online Published on 12 November, 2024.
Faecal microbiota transplantation (FMT) is a novel therapy in the field of gastroenterology which has been studied at current times with greater curiosity.
FMT was applied as an adjunct to symptomatic treatment in Canine Parvovirus (CPV) affected dogs for a period of 8 days once daily from the day of presentation. The results were compared with a similar group suffering from CPV infection maintained only on symptomatic treatment.
Response to FMT was evaluated on the basis of time taken for resolution of diarrhoea, time of hospitalization, scoring of clinical parameters, recurrence of gastroenteritis within 2 months post therapy of the two groups. Furthermore, adverse events and retention time of the transplant after the procedure were noted. It was observed that the 66.67% (4/6) dogs of FMT treated group had a quicker resolution of diarrhoea (mean 48 hours); FMT treated dogs had better clinical scores compared to symptomatic therapy group (score of 1 or clinically insignificant vs 4 or mildly diseased), lesser recurrence of diarrhoea 2 months post therapy in FMT treated group (16.67% vs 50%). Post FMT one case showed low grade fever (n=1) and epistaxis (n=1) respectively which resolved within 24 hours. The mean retention time of the transplant improved from (20.83±2.39) minutes to (140±12.66) on Day 7th of the trial (p<0.01). Faecal Microbiota Transplantation as an adjunct therapy might aid in early resolution of diarrhoea in acute diarrhoea in dogs.
Canine, Diarrhoea, FMT, Gastroenterology, IBD, Parvovirus, Veterinary
