1State Key Laboratory of Plateau Ecology and Agriculture/Academy of Animal Science and Veterinary Medicine, Qinghai University, Xining, 810016, China
2Key Laboratory of Livestock and Poultry Genetics and Breeding on the Qinghai-Tibet Plateau, Ministry of Agriculture and Rural Affairs, Xining, 810016, China
3Plateau Livestock Genetic Resources Protection and Innovative UtilizationKey Laboratory of Qinghai Province, Xining, 810016, China
*Corresponding Author: Sun Wu, Academy of Animal Science and Veterinary Medicine, Qinghai University, Xining, 810016, China, Email: sunwufrank@163.com
Online Published on 5 January, 2024.
It is not clear whether there are other motifs on the BMPIR gene in plateau-type Tibetan sheep and whether there is a strong association between the mutant locus and reproductive performance.
Single-nucleotide polymorphisms (SNPs) of the BMPRIB gene in the Tibetan sheep populations from the Qinghai pastoral area in China were detected by Sanger sequencing and performed correlation analysis with litter size.
Four SNPs (g.597 G>A, g.746 A>G, g.864 C>T and g.1113 C>A) of BMPRIB gene were firstly screened in Tibetan sheep. In loci g.746, relevance analysis discovered that genotypes GG and AG had 0.70 (P<0.05) and 0.79 (P<0.05) litter sizes more than the genotype AA in Tibetan sheep, respectively. In loci g.597, Tibetan sheep with genotypes AA and GA had 0.21 (P<0.05) and 0.31 (P<0.05) litter sizes more than the genotype GG, respectively. The results showed that g.746 A>G and g. 597 G>A were regarded as assisted-markers in molecular. These findings provide ideas and insights into the reproductive performance of Tibetan sheep in China.
BMPRIB, FecB, Litter size, Tibetan sheep
