Indian Journal of Animal Research
SCOPUSWeb of Science
  • Year: 2022
  • Volume: 56
  • Issue: 4

Determining Serum Haptoglobin and Proinflammatory Cytokines Concentration in the Calves Clinically Diagnosed with Pneumonitis, Pneumoenteritis and Enteritis

1Department of Internal Medicine, Faculty of Veterinary Medicine, Afyon Kocatepe University, Afyon Karahisar, Turkey.

2Department of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Afyon Kocatepe University, Afyon Karahisar-Turkey.

*Corresponding Author: M. Kabu, Department of Internal Medicine, Faculty of Veterinary Medicine, Afyon Kocatepe University, ANS Campus, 03200, Afyon Karahisar, Turkey, Email: mustafakabu@hotmail.com

Online Published on 09 May, 2022.

Abstract

This study aims to determine the concentration of serum haptoglobin (Hp), interleukin 1 (IL-1β), interleukin 6 (IL-6), and tumor necrosis factor-α (TNF-α) in cases of Pneumonia, Pneumoenteritis and Enteritis.

60 calves were subjected to the study and they were divided into four groups. The study group consisted of the claves diagnosed with clinical pneumonia (Group P; n=15), pneumoenteritis (Group PE; n=15) and enteritis (Group E; n=15) while the control group included the healthy calves (Group C; n=15). The measurements of the concentration of serum haptoglobin (Hp), interleukin 1 (IL-1β), interleukin 6 (IL-6) and tumor necrosis factor-α (TNF-α), Total protein (TP) and Albumin (ALB) were made by using commercial kits.

In all infection groups (P, PE ve E), Haptoglobin concentration, serum cytokine (IL-1β, IL-6 and TNF-α) and Albumin values were found to have been higher than the control group (p<0.005). However, there was no difference in total protein. In the light of these findings, it is suggested that routine controls for Haptoglobin and cytokine (IL-1β, IL-6 and TNF-α) concentrations would be rewarding to determine the severity of the infection, to choose the suitable treatment and to detect subclinical infections in veterinary medicine.

Keywords

Calf, Haptoglobin (Hp), Interleukin 1 (IL-1β), Interleukin 6 (IL-6), Tumor necrosis factor-α (TNF-α)