Indian Journal of Animal Research
SCOPUSWeb of Science
  • Year: 2021
  • Volume: 55
  • Issue: 5

Evaluation of the viricidal efficacy of four chemical disinfectants against emerged h7n9 avian influenza Virus in China

  • Author:
  • Sujuan Chen1,2,3*, Xinyu Miao1,4, Chuanwei Wang1, Tao Qin1,2,3, Daxin Peng1,2,3*
  • Total Page Count: 7
  • Page Number: 575 to 581

1College of Veterinary Medicine, Yangzhou University, Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou, Jiangsu225009, P.R.China

2Joint International Research Laboratory of Agriculture and Agri-Product Safety, The Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu225009, P.R.China

3Jiangsu Research Centre of Engineering and Technology for Prevention and Control of Poultry Disease, Yangzhou, Jiangsu225009, P.R.China

4These authors have contributed equally to this work

*Corresponding Author: Daxin Peng, College of Veterinary Medicine, Yangzhou University, Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou, Jiangsu225009, P.R.China, Email: pengdx@yzu.edu.cn

Online published on 22 July, 2021.

Abstract

Establishment of scientific disinfection measures in domestic poultry farms and live-poultry markets (LPMs) are critical to prevent the spread of H7N9 subtype avian influenza that outbreaks in poultry and infection in humans. The current study was aimed to evaluate the efficacy of four common disinfectants to inactivate H7N9 subtype avian influenza virus (AIV).

According to the disinfection technical specification, the average inactivation logarithmic values of four disinfectants against the epidemic H7N9 subtype AIV, including deciquam solution, glutaral and benzalkonium bromide solution, sodium dichloroisocyanurate powder, and peroxyacetic acid solution, were systematically evaluated.

Our data showed that incubation of 0.005% (w/v) deciquam solution for 30 min contact time, or 0.05% (v/v) glutaral and benzalkonium bromide solution for 10 min, or 0.24 g/L sodium dichloroisocyanurate powder for 30 min, or 0.05% (v/v) peroxyacetic acid solution for 10 min, can completely inactivate H7N9 subtype AIV. These results suggested that glutaral and benzalkonium bromide solution as well as peroxyacetic acid solution at recommended concentrations can be effectively used to cut off the spread of H7N9 subtype AIV in poultry farms and LPMs, however, deciquam solution and sodium dichloroisocyanurate powder need to increase their working concentration.

Keywords

Disinfectants, H7N9 avian influenza virus, Live-poultry markets, Poultry farms