Impact of supplementation of probiotic, prebiotic and synbiotic on serum biochemical profile of crossbred calves

A study was conducted on 24 fifteen day old crossbred calves that were divided into 4 groups of 6 calves each. The calves were fed different dietary treatments viz T₀ (control group)-basal diet, T₁ (probioticgroup)-basal diet + Lactobacillus acidophilus @ 1 g/calf/day(2 x 10¹⁰ cfu/g), T₂ (prebiotic group)_-basal diet + Mannan oligosaccharide (MOS) @ 4 g per calf/day and T₃ (synbiotic group) basal diet +Lactobacillus acidophilus @ 0.5 gm (2 x 10¹⁰ cfu/g) + 2 g MOS per calf/day respectively for a period of 90 days. Blood samples were taken at monthly interval and serum was separated to estimate different biochemical parameters. The results of study indicated that probiotic (Lactobacillus acidophilus), prebiotic (MOS) and synbiotic supplementation were effective in reduction of serum cholesterol and triglycerides at 60^th and 90^thday. Serum creatinine, glucose, urea and bilirubin were unaffected by dietary supplementation of probiotic, prebiotic (MOS) and synbiotic. There was noeffect of T₁, T₂ and T₃ supplementation on Serum enzymes, Aspartate aminotransferase(AST) and Alanine Amino Transferase (ALT).