Can Emblica officinalis and Tinospora cordifolia supplementation possess immunomodulatory and adaptogenic properties in murrah buffalo calves?

The present investigation was conducted to evaluate the combined effect of Emblica officinalis and Tinospora cordifolia supplementation on growth performance, hormonal and immune status in murrah buffalo calves. 14 day age unsupplementated 6 calves were taken as control, whereas 6 calves of treatment group were supplemented with combination of Emblica officinalis and Tinospora cordifolia (2: 1) @ 450 mg/kg body weight once a day orally for 28 days. The results indicated that, significant (p<0.05) higher body weight in treatment group as compare to control group. Serum cortisol concentration was significantly (p<0.05) lower in treatment group. Higher level of T₄ hormone, immunoglobulins and adaptability coefficient was observed in Emblica officinalis and Tinospora cordifolia treated group. It indicated that combination of Emblica officinalis and Tinospora cordifolia possess immunogenic effect and by inducing a state of non-specific increase in resistance to diverse climatic conditions they help to prevent calf mortality.