Light and ultra structural study of ileal peyer's patches in goat foetuses

By 94^th day rudimentary form of Peyer's Patches (PPs) appeared in the ilealsubmucosa and with advancing age it revealed lymphocytes, macrophage and few eosinophilic cells. In day old neonates PPs revealed secondary nodules with a predominance of lymphocyte, plasma cells, macrophages, reticular cells, RBCs etc. The collagen fibers and elastic fibers did not appear in outer thin fibrous covering of the ileal PP by 94 days of gestation. By 112 days few weakly reactive collagen fibers appeared at said location. With advancing age prominent and abundant reticular fibers were evident in the wall of arteriolar, capillaries and venules of the PP follicles and iliac submucosa as well as in lamina propria. Ultrastructuraly ilealpeyer's patches (PPs) revealed lymphocytes with elongated and ovoid nuclei. With advancing age medium and large lymphocytes appeared in a loose fashion. In day old neonates numerous and rapidly developing plasma cells were seen in the PP.