Nutritional and metabolic diseases associated with hepato - Renal pathology in chicken

Hepato-renal pathology associated with nutritional and metabolic diseases in chickens was studied using samples brought for autopsy to the Centre of Excellence in Pathology. Among these, fatty liver syndrome was observed in 41 chickens. The liver showed moderate to severe enlargement with yellowish to yellowish brown discoloration and hepatocytes were distended with fat vacuoles. Gout was observed in 18 chickens showing deposition of white chalky crystals on the visceral organs and joints. Microscopically the liver and kidneys showed urate deposition. Ascites syndrome was observed in 13 chickens with accumulation of clear yellowish fluid in the abdominal cavity. Histology of liver revealed multifocal random areas of necrosis and disorganization of hepatic cords. Kidney showed intertubular hemorrhages and degeneration.