*Lanzhou University, Lanzhou, 730 000,China
‡Lanzhou Institute of Animal Husbandry & Veterinary Pharmaceutics Sciences, Chinese Academy of Agricultural Sciences, Lanzhou, 730 050, China
+Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, 730050,China
§Corresponding author.
The study aims to investigate the efficacy of piroline and other antibiotics in the treatment of bovine mastitis caused by Streptococcus uberis and Escherichia coli during dry-milk period. A total of 1880 cows in dry-milk period were divided into 4 groups and treated with penicillin G, ammonia benzyl penicillin, ceftiofur and piroline, respectively. The efficac for mastitis caused by E. coli were 31.2% for penicillin G, 36.9% for ammonia benzyl penicillin, 61.3% for ceftiofur, and 64.4% for piroline. For mastitis caused by S. uberis, the efficacies are 90% for ceftiofur and 94.4% for piroline. The results indicated that piroline was more effective than the other three in treating the disease. The post-treatment analysis on milk samples demonstrated absence of piroline residue. Hence, piroline could be used as therapeutic agent in treating mastitis.
Piroline, bovine mastitis, efficacy