Indian Veterinary Research Institute, Izatnagar-243 122, India.
*A part of the M. V. Sc. Thesis submitted to the Indian Veterinary Research Institute, Izatnagar (UP).
White leghorn (IWJ, IWG and IWC) embryos of 11-day-old were inoculated via the chorioallantoic membrane (CAM) route with 0.2 ml of subgroup A and C Rous sarcoma viruses (RSVs), separately containing 103 pfu/ml. Eggs were further incubated for hatching. The distribution of tumour lesions in different organs was categorized in accordance with the pock count ranges (PCRs) and days of survival. The liver was the target organ for the virus-induced cellular transformation for the avian species because of the higher frequency and first appearance. The study conducted to investigate the distribution pattern of visceral metastasis in subgroup A and C viral infection revealed that liver was the most affected visceral organ followed by heart, lungs, spleen, kidney and gonads. The bursa of Fabricius and thymus were found to be tumour negative.
