Formulation and Evaluation of Fast Dissolving Tablets of Pioglitazone

The purpose of this research work to formulate and evaluate fast dissolving tablets of pioglitazone. Tablets containing pioglitazone, sodium starch glycolate & crospovidone were prepared by direct compression technique. The total five batches were prepared (F1-F5) and evaluated for friability, hardness, thickness, in-vitro disintegration and dissolution studies. Formulations F4 showed minimum disintegration time of 53 sec and maximum drug release. Tablets containing sodium starch glycolate along with crospovidone is showing excellent results as compare to other formulations.