Formulation, Development and Evaluation of Expectorant Extended Release Tablet

The formulation and development of extended released tablet of Guaifenesin was developed. The matrix tablet was formulated of drug. The preformulation study guaifenesin with polymer were studies and HPMC was used for formulation of matrix tablet. The granules formulated for making matrix tablet were evaluated for bulk density and tapped density. The compressed matrix tablet of guaifenesin, were evaluated for weight variation, thichness, hardness, content uniformity and in vitro released studies.