Comparative Studies on Sedimentation Parameter of Aluminium Hydroxide and Sodium Bicarbonate, Magnesium Trisilicate, Magnesium Carbonate Suspension

The sedimentation volume (F) is defined as the ratio of final or ultimate volume to the suspension volume. If the volume of sedimentation in a flocculated suspension equal to the original volume of suspension, then F=1 is pharmaceutically acceptable. When F=0 it means the total drug has sedimented and volume of sediment is negligible. So, more the volume of F more will be therapeutic acceptance. In this study two types of suspension were studied where aluminium hydroxide suspension classed as type-I and sodium-bi-carbonate, magnesium trisilicate, magnesium carbonate suspension classed as ty pe-II suspension. It was observed that the sedimentation volume is more in case of type-I suspension rather than type-II suspension.