Asian Journal of Pharmacy and Technology
  • Year: 2026
  • Volume: 16
  • Issue: 2

A review on Dysbiosis: Diagnosis, Biomarker Identification, and Herbal Therapies, Celosia Cristata

  • Author:
  • Anjum Hamid Khan*, Laxmikant Purane, Abhirup Sagare, Sanchita Borate, Sunita Wanjale, Prachi Pawar
  • Total Page Count: 12
  • Page Number: 207 to 218

Department of Pharmacology, Yashoda Technical Campus, Satara, Dr. Babasaheb Ambedkar Technological University, Lonare402103, Maharashtra, India.

*Corresponding Author E-mail: anjumhkhan8@gmail.com

Abstract

In addition to biomarkers with detection tests like ELISA (enzyme-linked immunosorbent assay), diabetes mellitus, gut dysbiosis, an imbalance in gut microbiota, cytokines (IL-6), cytokines (TNF-α), cytokines (IL-10), C-reactive protein (CRP), calprotectin, zonulin, LPS-binding protein, and lipopolysaccharide (LPS). By restoring equilibrium through a variety of substances and plants, including aloe vera, fennel, ginger, dandelion, green tea, etc., as well as phytochemicals like phenols, tannins, flavonoids, curcumin, etc., herbal therapies offer promise modulation. Polyphenols from green tea and aloe vera increase beneficial bacteria like Bifidobacterium, reduce harmful pathogens, strengthen the intestinal barrier, and encourage the production of short-chain fatty acids (SCFAs), according to data from animal studies and clinical assessments. This all-encompassing strategy makes it easier for researchers creating novel herbal medications to cure dysbiosis. Ginger and other tried-and-true herbs are summarized in this article. Celosia cristata, or cockscomb, may satisfy the requirements of dysbiosis by removing or otherwise addressing problems related to the dysbiosis and possessing flavonoids, despite the lack of studies on microbiota alterations, SCFAs, or gut barrier models. This study does not test this plant. This author has started a new study (ongoing work) using floral extracts to close the gap.

Keywords

Dysbiosis, Biomarkers, Biomarker Identification, Herbal Plant, Phytochemical, Celosia Cristata (Cockscomb) in Dysbiosis