Formulation and Therapeutic Evaluation of Tinospora cordifolia-Infused Cream for the Management of Acute wounds

The present study focuses on the formulation and evaluation of a topical cream containing Tinospora cordifolia extract for the management of acute wounds. Tinospora cordifolia, a medicinal plant known for its antimicrobial, anti-inflammatory, and antioxidant properties, was incorporated into a cream base to enhance wound healing. The cream was evaluated for its physicochemical properties, including pH, viscosity, spreadability, and stability. In vitro antimicrobial activity was assessed using the disc diffusion method, while antioxidant potential was measured using the DPPH assay. The cream’s wound healing efficacy was further investigated through in vivo studies using a rat wound model. The results revealed that the cream demonstrated significant antimicrobial activity against common wound pathogens and exhibited strong antioxidant properties. In vivo studies showed accelerated wound closure, enhanced collagen deposition, and reduced inflammatory cytokine levels, indicating effective wound healing. These findings suggest that the Tinospora cordifolia-infused cream is a promising alternative for acute wound treatment, with the potential for further clinical applications.